serum uric acid as a potential concomitant with carotid atherosclerosis

background: common carotid intima-media thickness (cc-imt) measured by ultrasonography as a non-invasive method is nowadays known as a marker for early atherosclerosis. objectives: survey the relationship between serum uric acid and carotid intima-media thickness considering hypertension. materials and methods: this study was designed as a comparative cross-sectional study in northern iran in 2013–2014. the samples for uric acid level were taken from 90 patients. data were collected through questionnaires and a non-invasive ultrasound technique was used to measure imt. the analysis of data was done by one-way anova and tukey post hoc tests and logistic regression model using spss software version 21. the significance level was set as 0.05. results: patients in the 3 groups were the same age and gender. the measured carotid intima-media thickness was significantly different among the groups (p=0.004). using multivariate logistic regression and entering all variables, the intima-media thickness of the carotid in the group with hypertensive and hyperuricemia was significantly higher than that of the other research groups (p<0.05). conclusion: an association was found between serum uric acid level and increased thickness of carotid intima-media and hyperuricemia can be considered as a risk factor for atherosclerosis.